Article
The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention.
Seminars in radiation oncology - 1 Oct 2015
Kerns Sarah L, Kundu Suman, Oh Jung Hun, Singhal Sandeep K, Janelsins Michelle, Travis Lois B, Deasy Joseph O, Janssens A Cecile J E, Ostrer Harry, Parliament Matthew, Usmani Nawaid, Rosenstein Barry S
Abstract excerpt
Radiotherapy is a mainstay of cancer treatment, used in either a curative or palliative manner to treat approximately 50% of patients with cancer. Normal tissue toxicity limits the doses used in standard radiation therapy protocols and impedes improvements in radiotherapy efficacy. Damage to surrounding normal tissues can produce reactions ranging from bothersome symptoms that negatively affect quality of life to...
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