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Article

Predicting the germline dependence of hematuria risk in prostate cancer radiotherapy patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Aug 2023

Oh Jung Hun, Lee Sangkyu, Thor Maria, Rosenstein Barry S, Tannenbaum Allen, Kerns Sarah, Deasy Joseph O

Abstract excerpt

BACKGROUND AND PURPOSE: Late radiation-induced hematuria can develop in prostate cancer patients undergoing radiotherapy and can negatively impact the quality-of-life of survivors. If a genetic component of risk could be modeled, this could potentially be the basis for modifying treatment for high-risk patients. We therefore investigated whether a previously developed machine learning-based modeling method using...

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Ferroptosis and cancer prognosis
Genome-Wide Association Study
Germ Cells
Hematuria
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostate Cancer Diagnosis and Treatment

Prostatic Neoplasms

Urinary Bladder

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Identifiers

PMID: 37244355
DOI: 10.1016/j.radonc.2023.109723
PMCID: PMC10524941

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