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Article

Genomic profiling of esophageal squamous cell carcinoma (ESCC)-Basis for precision medicine.

Pathology, research and practice - 1 Jul 2017

Yang Jung Wook, Choi Yoon-La

Abstract excerpt

PURPOSE: Preparing for precision medicine, we surveyed genomic alterations in esophageal squamous cell carcinoma (ESCC) and identified candidate therapeutic targets by genomic profiling using next-generation sequencing (NGS). MATERIALS AND METHODS: Single-nucleotide variations, indels, and copy number variations in 80 genes were evaluated by targeted deep sequencing in 24 surgically resected ESCC specimens....

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28554745
DOI: 10.1016/j.prp.2017.02.021

Genes

ERBB2
EGFR
NOTCH1
AKT2
FGFR1
KRAS
MDM2
MTOR

Provenance

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