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Article

Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.

The Annals of thoracic surgery - 1 Apr 2012

Bandla Santhoshi, Pennathur Arjun, Luketich James D, Beer David G, Lin Lin, Bass Adam J, Godfrey Tony E, Litle Virginia R

Abstract excerpt

BACKGROUND: Esophageal cancer consists of two major histologic types: esophageal squamous cell carcinoma (ESCC), predominant globally, and esophageal adenocarcinoma (EAC), which has a higher incidence in westernized countries. Five-year overall survival is 15%. Clinical trials frequently combine histologic types although they are different diseases with distinct origins. In the evolving era of personalized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22450065
DOI: 10.1016/j.athoracsur.2012.01.064
PMCID: PMC3401935

Genes

CDK6
EGFR
ERBB2
FGFR1
KRAS
MET
MYC
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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