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Article

Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Mar 2017

Läll Kristi, Mägi Reedik, Morris Andrew, Metspalu Andres, Fischer Krista

Abstract excerpt

PURPOSE: Using effect estimates from genome-wide association studies (GWAS), we identified a genetic risk score (GRS) that has the strongest association with type 2 diabetes (T2D) status in a population-based cohort and investigated its potential for prospective T2D risk assessment. METHODS: By varying the number of single-nucleotide polymorphisms (SNPs) and their respective weights, alternative versions of GRS...

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Identifiers

PMID: 27513194
DOI: 10.1038/gim.2016.103
PMCID: PMC5506454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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