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Genetic risk score constructed from common genetic variants is associated with cardiovascular disease risk in type 2 diabetes mellitus.

The journal of gene medicine - 1 Feb 2021

Cheng Chi-Fung, Lin Ying-Ju, Lin Mei-Chen, Liang Wen-Miin, Chen Ching-Chu, Chen Chien-Hsiun, Wu Jer-Yuarn, Lin Ting-Hsu, Liao Chiu-Chu, Huang Shao-Mei, Hsieh Ai-Ru, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Patients with type 2 diabetes mellitus (T2DM) experience a two-fold increased risk of cardiovascular diseases. Genome-wide association studies (GWAS) have identified T2DM susceptibility genetic variants. Interestingly, the genetic variants associated with cardiovascular disease risk in T2DM Han Chinese remain to be elucidated. The present study aimed to investigate the genetic variants associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33350037
DOI: 10.1002/jgm.3305

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