Article
Improved genetic risk scoring algorithm for type 1 diabetes prediction.
Pediatric diabetes - 1 May 2022
Qu Hui-Qi, Qu Jingchun, Glessner Joseph, Liu Yichuan, Mentch Frank, Chang Xiao, March Michael, Li Jin, Roizen Jeffrey D, Connolly John J, Sleiman Patrick, Hakonarson Hakon
Abstract excerpt
BACKGROUND: Precise risk prediction of type 1 diabetes (T1D) facilitates early intervention and identification of risk factors prior to irreversible beta-islet cell destruction, and can significantly improve T1D prevention and clinical care. Sharp et al. developed a genetic risk scoring (GRS) system for T1D (T1D-GRS2) capable of predicting T1D risk in children of European ancestry. The T1D-GRS2 was developed on...
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