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Differences in DNA damage repair gene mutations between left- and right-sided colorectal cancer.

Cancer medicine - 1 May 2023

Huang Wei, Li Wenliang, Xu Ning, Li Hui, Zhang Zihan, Zhang Xiaolong, He Tingting, Yao Jicheng, Xu Mian, He Qingqing, Guo Lijie, Zhang Sen

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. Studies have shown that the DNA damage response (DDR) mutation is strongly associated with microsatellite instability (MSI) status and is an indication for patients with CRCs receiving immune checkpoint inhibitor (ICI) treatment. However, DDR mutation in microsatellite stable (MSS) CRC remains unclear. METHODS: In...

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Identifiers

PMID: 37096801
DOI: 10.1002/cam4.5716
PMCID: PMC10225210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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