Article
Molecular Analyses of Left- and Right-Sided Tumors in Adolescents and Young Adults with Colorectal Cancer.
The oncologist - 1 May 2020
Salem Mohamed E, Battaglin Francesca, Goldberg Richard M, Puccini Alberto, Shields Anthony F, Arguello David, Korn W Michael, Marshall John L, Grothey Axel, Lenz Heinz-Josef
Abstract excerpt
BACKGROUND: The incidence of colorectal cancer (CRC), particularly left-sided tumors (LT), in adolescents and young adults (AYA) is rising. Epigenetic events appear to play an important role in tumorigenesis and cancer progression, especially in younger patients. We compared molecular features of LT to right-sided tumors (RT) in AYA. MATERIALS AND METHODS: A total of 246 LT and 56 RT were identified in a cohort...
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