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Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer

1 Dec 2015

Abstract excerpt

BACKGROUND: Aberrant DNA methylation has been widely investigated in sporadic colorectal carcinomas (CRCs), and extensive work has been performed to characterize different methylation profiles of CRC. Less information is available about the role of epigenetics in hereditary CRC and about the possible clinical use of epigenetic biomarkers in CRC, regardless of the etiopathogenesis. Long interspersed nucleotide...

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PMID: 26697123
DOI: 10.1186/s13148-015-0165-2

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