Article
Right Versus Left Colon Cancer Biology: Integrating the Consensus Molecular Subtypes.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Mar 2017
Lee Michael S, Menter David G, Kopetz Scott
Abstract excerpt
Although clinical management of colon cancer generally has not accounted for the primary tumor site, left-sided and right-sided colon cancers harbor different clinical and biologic characteristics. Right-sided colon cancers are more likely to have genome-wide hypermethylation via the CpG island methylator phenotype (CIMP), hypermutated state via microsatellite instability, and BRAF mutation. There are also...
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