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Article

A Functional Polymorphism (rs937283) in the MDM2 Promoter Region is Associated with Poor Prognosis of Retinoblastoma in Chinese Han Population.

Scientific reports - 10 Aug 2016

Jiao Yongfa, Jiang Zhongming, Wu Yuxia, Chen Xiaochong, Xiao Xing, Yu Haiying

Abstract excerpt

The effect of single nucleotide polymorphisms (SNPs) at MDM2 has been investigated in several cancer types. Three MDM2 SNPs(rs937283, rs2270744 and rs769412) have previously been suggested to be positively correlated with cancer. In this study, we aimed to explore the association of rs937283, rs2270744 and polymorphisms with retinoblastoma (RB) risk, clinicopathological characteristics, and prognosis....

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Source

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Identifiers

PMID: 27506496
DOI: 10.1038/srep31240
PMCID: PMC4979029

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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