Article

MicroRNA-532 inhibits cell growth and metastasis in retinoblastoma by targeting MDM4

2020-05-01

Abstract excerpt

<title>Abstract</title> <p>Background Now, numerous microRNAs (miRNAs) are found to exert effect in retinoblastoma (RB). This research mainly focused on the function of miR-532 in RB, which has not been investigated. Methods RT-qPCR and Western blot analysis were used to measure expressions of miR-532 and genes. Transwell, CCK-8 and luciferase reporter assays were applied to explore functions of miR-532 and MDM...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90a6d9cf-71f3-5e7e-82ed-71545d32165e
DOI: 10.21203/rs.3.rs-25023/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-532 inhibits cell growth and metastasis in retinoblastoma by targeting MDM4DOI 10.21203/rs.3.rs-25023/v1Read

miR-491-3p is Downregulated in Retinoblastoma and Inhibit Tumor Cells Growth and Metastasis by Targeting SNNSemantic proximity Read

miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses.Semantic proximity Read

MicroRNAs in retinoblastoma: Potential diagnostic and therapeutic biomarkersSemantic proximity Read

miR-29a inhibits human retinoblastoma progression by targeting STAT3Semantic proximity Read

Roles of the microRNA‑338‑3p/NOVA1 axis in retinoblastoma.Semantic proximity Read

Targeting MDM2 and MDMX in RetinoblastomaSemantic proximity Read

MicroRNA-98 targets HMGA2 to inhibit the development of retinoblastoma through mediating Wnt/β-catenin pathwaySemantic proximity Read

MiR-433 inhibits retinoblastoma malignancy by suppressing Notch1 and PAX6 expressionSemantic proximity Read

Circ_0000527 promotes the progression of retinoblastoma by regulating miR-646/LRP6 axisSemantic proximity Read

Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysisSemantic proximity Read

miR-214-3p Regulates Multi-Drug Resistance and Apoptosis in Retinoblastoma Cells by Targeting ABCB1 and XIAPSemantic proximity Read

LncRNA HOTAIR facilitates proliferation and represses apoptosis of retinoblastoma cells through the miR-20b-5p/RRM2/PI3K/AKT axisSemantic proximity Read