Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative Transcriptome Profiling of Human Foreskin Fibroblasts Infected with the Sylvio and Y Strains of Trypanosoma cruzi

9 Aug 2016

Abstract excerpt

Trypanosoma cruzi, the causative agent of Chagas Disease, is phylogeneticaly distributed into nearly identical genetic strains which show divergent clinical presentations including differences in rates of cardiomyopathy in humans, different vector species and transmission cycles, differential congenital transmission in a mouse model, and differing immune and heart inflammation response in dogs. The population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27505626
DOI: 10.1371/journal.pone.0159197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative Transcriptome Profiling of Human Foreskin Fibroblasts Infected with the Sylvio and Y Strains of Trypanosoma cruziPMID 27505626Read ↗

Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi InfectionSemantic proximity Read ↗

Single-Cell Targeted Transcriptomics Reveals Subset-Specific Immune Signatures Differentiating Asymptomatic and Cardiac Patients With Chronic Chagas DiseaseSemantic proximity Read ↗

Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruziSemantic proximity Read ↗

Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactionsSemantic proximity Read ↗

The <i>Trypanosoma cruzi</i> cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiationSemantic proximity Read ↗

Determinants of disease phenotype in trypanosomatid parasites.Semantic proximity Read ↗

Chagas Disease Cardiomyopathy: Immunopathology and GeneticsSemantic proximity Read ↗

Stochastic variation in surface protein expression diversifies <i>Trypanosoma cruzi</i> infectionSemantic proximity Read ↗

Gene Expression Changes Associated with Myocarditis and Fibrosis in Hearts of Mice with Chronic Chagasic CardiomyopathySemantic proximity Read ↗

Cardiomyocyte transcriptomic signatures in response to <i>Trypanosoma cruzi</i> infection underpin Chagas cardiomyopathy progressionSemantic proximity Read ↗

Differential modulation of mouse heart gene expression by infection with two <i>Trypanosoma cruzi</i> strains: a transcriptome analysisSemantic proximity Read ↗

Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular DysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.