Article
Determinants of disease phenotype in trypanosomatid parasites.
Trends in parasitology - 1 Jul 2014
McCall Laura-Isobel, McKerrow James H
Abstract excerpt
Trypanosomatid parasites infect over 21 million people worldwide, with a range of disease phenotypes. Trypanosoma cruzi causes American trypanosomiasis, wherein 30-40% of infected individuals develop disease manifestations, most commonly cardiomyopathy but also digestive megasyndromes. In the case of Trypanosoma brucei, the etiological agent of African trypanosomiasis, disease progression can be rapid or slow,...
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