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Cardiomyocyte transcriptomic signatures in response to <i>Trypanosoma cruzi</i> infection underpin Chagas cardiomyopathy progression

2023-03-03

Abstract excerpt

Chagas disease can lead to life-threatening cardiac manifestations that occur more frequently in geographic areas more prevalent with the TcI/II circulating genetic strains. To elucidate the differential transcriptomic signatures of the cardiomyocyte resulting from infection with TcI/II or TcVI T. cruzi strains and explore their relationships with pathogenesis, HL-1 rodent cardiomyocytes were infected with TcI/II...

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Literature Corpus work
a0eace1f-5b2b-56ec-95ed-227809801818
DOI
10.1101/2023.02.27.530371
Open publication

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Cardiomyocyte transcriptomic signatures in response to <i>Trypanosoma cruzi</i> infection underpin Chagas cardiomyopathy progressionDOI 10.1101/2023.02.27.530371
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