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Article

Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction

29 Nov 2016

Abstract excerpt

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects 7 million people in Latin American areas of endemicity. About 30% of infected patients will develop chronic Chagas cardiomyopathy (CCC), an inflammatory cardiomyopathy characterized by hypertrophy, fibrosis, and myocarditis. Further studies are necessary to understand the molecular mechanisms of disease progression. Transcriptome analysis...

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PMID: 28003350
DOI: 10.1093/infdis/jiw540

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