Article
Haploidentical and Matched Sibling Donor Hematopoietic Cell Transplantation for Patients with HLA-Homozygous Haplotypes.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Nov 2016
Kanda Junya, Ikegame Kazuhiro, Fuji Shigeo, Kurokawa Mineo, Kanamori Heiwa, Fukuda Takahiro, Ohashi Kazuteru, Ishikawa Jun, Ogawa Hiroyasu, Inoue Masami, Ichinohe Tatsuo, Atsuta Yoshiko, Kanda Yoshinobu
Abstract excerpt
More than 1% of the Japanese population has HLA-homozygous haplotypes. For patients with such haplotypes, HLA-haploidentical family members who have no HLA mismatch in the graft-versus-host direction are readily available donor candidates for hematopoietic cell transplantation (HCT). In this study, the outcomes of patients with homozygous HLA-A, -B, and -DRB1 antigens who received HCT without T cell depletion...
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