Transfusion‐associated graft‐versus‐host disease: risk due to homozygous HLA haplotypes

doi:10.1046/j.1537-2995.1995.35495216075.x

Article

Transfusion‐associated graft‐versus‐host disease: risk due to homozygous HLA haplotypes

1 Apr 1995

Abstract excerpt

BACKGROUND: Transfusion-associated graft-versus-host disease (TA-GVHD) may occur in transfusions of blood from HLA-homozygous persons to HLA-heterozygous persons who share a haplotype. STUDY DESIGN AND METHODS: Two mathematical models were developed to calculate the upper and lower limit of the associated risks in various populations using a combination of serology- and DNA sequence-based HLA haplotype...

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