Article
Risk of HLA Homozygous Cord Blood Transplantation: Implications for Induced Pluripotent Stem Cell Banking and Transplantation.
Stem cells translational medicine - 1 Feb 2018
Morishima Yasuo, Azuma Fumihiro, Kashiwase Koichi, Matsumoto Kayoko, Orihara Takeshi, Yabe Hiromasa, Kato Shunichi, Kato Koji, Kai Shunro, Mori Tetsuo, Nakajima Kazunori, Morishima Satoko, Satake Masahiro, Takanashi Minoko, Yabe Toshio
Abstract excerpt
Clinical application of induced pluripotent stem cells (iPS) in autologous settings has just begun. To overcome the high time and cost barriers in the individual production of autologous iPS, the use of allogeneic iPS with a homozygous human leukocyte antigen (HLA) haplotype (HLA-homo HP) has been proposed. Cord blood transplantation (CBT) is a suitable model for evaluating the allogeneic immunogenicity of iPS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
