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HLA class I supertypes and HLA class I alleles influence the outcome after allogeneic hematopoietic stem cell transplant from unrelated matched donor.

Transplant immunology - 1 Feb 2025

Grubic Zorana, Burek Kamenaric Marija, Maskalan Marija, Desnica Lana, Mikulic Mirta, Stingl Jankovic Katarina, Durakovic Nadira, Vrhovac Radovan, Serventi Seiwerth Ranka, Zunec Renata

Abstract excerpt

This retrospective study analyses the impact HLA heterozygosity, supertypes, and alleles have on incidence of graft versus host disease (GvHD), relapse, overall survival (OS), disease-free survival (DFS) and transplant-related mortality (TRM) after HSCT. The study included patients who underwent HSCT, typed at allele resolution level for HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1 loci. The analysis performed on the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39716646
DOI: 10.1016/j.trim.2024.102167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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