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Article

Molecular disparity in human leukocyte antigens is associated with outcomes in haploidentical stem cell transplantation

29 Jul 2020

Abstract excerpt

Haploidentical donors are increasingly used for patients requiring hematopoietic stem cell transplantation (HSCT). Although several factors have been associated with transplant outcomes, the impact of HLA disparity in haploidentical HSCT (haplo-HSCT) remains unclear. We investigated the impact of HLA disparity quantified by mismatched eplets (ME) load of each HLA locus on the clinical outcome of 278 consecutive...

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PMID: 32726398
DOI: 10.1182/bloodadvances.2019000797

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