Population genetics of IFITM3 in Portugal and Central Africa reveals a potential modifier of influenza severity.

doi:10.1007/s00251-017-1026-2

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Article

Population genetics of IFITM3 in Portugal and Central Africa reveals a potential modifier of influenza severity.

Immunogenetics - 1 Mar 2018

David Susana, Correia Vanessa, Antunes Liliana, Faria Ricardo, Ferrão José, Faustino Paula, Nunes Baltazar, Maltez Fernando, Lavinha João, Rebelo de Andrade Helena

Abstract excerpt

Influenza epidemics are a serious global public health and economic problem. The IFITM3 allele (rs12252-C) was suggested as a population-based genetic risk factor for severe influenza virus infection by A(H1N1)pdm09. We analyzed the population genetics of IFITM3 variants in the Portuguese general population (n = 200) and Central Africans (largely Angolan) (n = 148) as well as its association to influenza severity...

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Identifiers

PMID: 28842783
DOI: 10.1007/s00251-017-1026-2

Genes

IFITM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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