Article
IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Pan Yang, Yang Peng, Dong Tao, Zhang Yi, Shi Weixian, Peng Xiaomin, Cui Shujuan, Zhang Daitao, Lu Guilan, Liu Yimeng, Wu Shuangsheng, Wang Quanyi
Abstract excerpt
Background: Interferon Inducible Transmembrane 3 (IFITM3) is a key factor in interferon pathway and it involves host's immune response against multiple viruses. IFITM3 rs12252-C was associated with severe influenza virus infection in several studies, however whether this association is universal to all types of influenza virus or diverse ethnic populations remain controversial. Method: A case-control genetic...
Topics
- Adolescent
- Adult
- Aged
- Case-Control Studies
- China
- Communicable Diseases
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Humans