Article
Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish.
Cell biochemistry and function - 1 Aug 2016
Raghupathy Rakesh K, Zhang Xun, Alhasani Reem H, Zhou Xinzhi, Mullin Margaret, Reilly James, Li Wenchang, Liu Mugen, Shu Xinhua
Abstract excerpt
Photoreceptors are highly specialized sensory neurons that possess a modified primary cilium called the outer segment. Photoreceptor outer segment formation and maintenance require highly active protein transport via a process known as intraflagellar transport. Anterograde transport in outer segments is powered by the heterotrimeric kinesin II and coordinated by intraflagellar transport proteins. Here, we...
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