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Article

Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins.

Genetics - 1 Jun 2016

Pooranachandran Niedharsan, Malicki Jarema J

Abstract excerpt

Transport of proteins in the ciliary shaft is driven by microtubule-dependent motors, kinesins. Prior studies suggested that the heterotrimeric ciliary kinesin may be dispensable for certain aspects of transport in specialized cilia of vertebrate photoreceptor cells. To test this possibility further, we analyzed the mutant phenotype of the zebrafish kif3a gene, which encodes the common motor subunit of...

Topics

Animals
Basal Bodies
Cilia
Flagella
Kinesins
Mutation
Phenotype
Photoreceptor Cells, Vertebrate
Protein Transport
Zebrafish
Zebrafish Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27038111
DOI: 10.1534/genetics.115.180943
PMCID: PMC4896193

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