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Article

Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre.

Investigative ophthalmology & visual science - 1 Nov 2006

Jimeno David, Feiner Leonard, Lillo Concepcion, Teofilo Karen, Goldstein Lawrence S B, Pierce Eric A, Williams David S

Abstract excerpt

PURPOSE: To determine the relationship between the presence of kinesin-2 and photoreceptor cell viability and opsin transport, by generating RHO-Cre transgenic mice and breeding them to mice with a floxed kinesin-2 motor gene. METHODS: Different lines of RHO-Cre transgenic mice were generated and characterized by transgene expression, histology, and electrophysiology. Mice from one line, showing uniform transgene...

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Source

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Identifiers

PMID: 17065525
DOI: 10.1167/iovs.06-0032
PMCID: PMC1904505

Genes

RHO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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