Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early defects in photoreceptor outer segment morphogenesis in zebrafish ift57, ift88 and ift172 Intraflagellar Transport mutants.

Vision research - 1 Feb 2009

Sukumaran Sujita, Perkins Brian D

Abstract excerpt

Intraflagellar Transport (IFT) refers to a highly conserved process occurring in eukaryotic ciliated structures. In vertebrate photoreceptors, IFT mediates protein trafficking to the outer segments. The IFT particle is a multi-subunit complex and mutations in many individual components causes photoreceptor defects. In zebrafish, mutations in the ift57, ift88, and ift172 genes result in retinal degeneration by 5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Microscopy, Electron, Transmission

Share to Morphogenesis

Share to Time Factors

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19136023
DOI: 10.1016/j.visres.2008.12.009
PMCID: PMC2674962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early defects in photoreceptor outer segment morphogenesis in zebrafish ift57, ift88 and ift172 Intraflagellar Transport mutants.PMID 19136023Read ↗

Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia.Semantic proximity Read ↗

The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors.Semantic proximity Read ↗

Ift172 conditional knock-out mice exhibit rapid retinal degeneration and protein trafficking defects.Semantic proximity Read ↗

Review: Intraflagellar transport proteins in the retina.Semantic proximity Read ↗

Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport.Semantic proximity Read ↗

<i>Ift172</i> conditional knockout mice exhibit rapid retinal degeneration and protein trafficking defectsSemantic proximity Read ↗

Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons.Semantic proximity Read ↗

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy.Semantic proximity Read ↗

TMEM216 Deletion Causes Mislocalization of Cone Opsin and Rhodopsin and Photoreceptor Degeneration in Zebrafish.Semantic proximity Read ↗

Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish.Semantic proximity Read ↗

Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degenerationSemantic proximity Read ↗

IFT20 is required for opsin trafficking and photoreceptor outer segment developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.