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Article

Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2016

Hale Gillian, Liu Xinxin, Hu Junjie, Xu Zhong, Che Li, Solomon David, Tsokos Christos, Shafizadeh Nafis, Chen Xin, Gill Ryan, Kakar Sanjay

Abstract excerpt

The current clinical practice is based on the assumption of strong correlation between diffuse glutamine synthetase expression and β-catenin activation in hepatocellular adenoma and hepatocellular carcinoma. This high correlation is based on limited data and may represent an oversimplification as glutamine synthetase staining patterns show wide variability in clinical practice. Standardized criteria for...

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Share to Adenoma, Liver Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27469330
DOI: 10.1038/modpathol.2016.122
PMCID: PMC5149418

Genes

CTNNB1

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