Article
Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC.
Hepatology (Baltimore, Md.) - 1 Mar 2006
Zucman-Rossi Jessica, Jeannot Emmanuelle, Nhieu Jeanne Tran Van, Scoazec Jean-Yves, Guettier Catherine, Rebouissou Sandra, Bacq Yannick, Leteurtre Emmanuelle, Paradis Valérie, Michalak Sophie, Wendum Dominique, Chiche Laurence, Fabre Monique, Mellottee Lucille, Laurent Christophe, Partensky Christian, Castaing Denis, Zafrani Elie Serge, Laurent-Puig Pierre, Balabaud Charles, Bioulac-Sage Paulette
Abstract excerpt
Hepatocellular adenomas are benign tumors that can be difficult to diagnose. To refine their classification, we performed a comprehensive analysis of their genetic, pathological, and clinical features. A multicentric series of 96 liver tumors with a firm or possible diagnosis of hepatocellular adenoma was reviewed by liver pathologists. In all cases, the genes coding for hepatocyte nuclear factor 1alpha...
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