Article
Hepatocellular Carcinoma with β-Catenin Mutation: Imaging and Pathologic Characteristics.
Radiology - 1 Jun 2015
Kitao Azusa, Matsui Osamu, Yoneda Norihide, Kozaka Kazuto, Kobayashi Satoshi, Sanada Junichiro, Koda Wataru, Minami Tetsuya, Inoue Dai, Yoshida Kotaro, Yamashita Taro, Yamashita Tatsuya, Kaneko Shuichi, Takamura Hiroyuki, Ohta Tetsuo, Ikeda Hiroko, Nakanuma Yasuni, Kita Ryuichi, Gabata Toshifumi
Abstract excerpt
PURPOSE: To identify the imaging features of hepatocellular carcinoma (HCC) associated with β-catenin mutation and their relationship to pathologic findings. MATERIALS AND METHODS: Institutional ethics committee approval and informed consent were obtained. One hundred thirty-eight surgically resected HCCs were analyzed in this study. Immunohistochemical expression of β-catenin and its transcriptional product,...
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