Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac

26 Jul 2016

Abstract excerpt

BACKGROUND: Claudin-6 (CLDN6), a member of claudin transmembrane protein family, has recently been reported to be undetectable or at low levels in human breast cancer cell lines and tissues and plays a role in suppression of migration and invasion in breast cancer cells. In addition, it is reported that CLDN6 expression is regulated by DNA methylation in various human cancers and cell lines. However, it is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Barrier Structure and Function Studies
Share to Caveolin-1 and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27461117
DOI: 10.1186/s13046-016-0396-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4AcPMID 27461117Read ↗

CLDN6: From Traditional Barrier Function to Emerging Roles in CancersSemantic proximity Read ↗

CLDN6 promotes chemoresistance through GSTP1 in human breast cancerSemantic proximity Read ↗

Identification of Claudin-6 as a Molecular Biomarker in Pan-Cancer Through Multiple Omics Integrative AnalysisSemantic proximity Read ↗

The Expression of CLDN6 in Hepatocellular Carcinoma Tissue and the Effects of CLDN6 on Biological Phenotypes of Hepatocellular Carcinoma CellsSemantic proximity Read ↗

Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-BSemantic proximity Read ↗

Hypomethylation of CLDN4 Gene Promoter Is Associated with Malignant Phenotype in Urinary Bladder Cancer.Semantic proximity Read ↗

A SUMOylation-dependent HIF-1α/CLDN6 negative feedback mitigates hypoxia-induced breast cancer metastasisSemantic proximity Read ↗

Tight junction protein, claudin-6, downregulates the malignant phenotype of breast carcinoma.Semantic proximity Read ↗

The Expression And The Tumor Suppressor Role of CLDN6 In Colon CancerSemantic proximity Read ↗

Aberrant claudin-6–adhesion signal promotes endometrial cancer progression via estrogen receptor αSemantic proximity Read ↗

CCN6 (WISP3) as a new regulator of the epithelial phenotype in breast cancer.Semantic proximity Read ↗

Silencing of Claudin-11 Is Associated with Increased Invasiveness of Gastric Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.