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Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

30 Sept 2018

Abstract excerpt

BACKGROUD: Dysregulation of claudin-6 (CLDN6) expression in cancers has been widely documented. However, no study has reported a complete mechanistic understanding of CLDN6 regulation and function in endometrial carcinoma (EC) progression. In the current study, we aimed to assess the expression and biological functions of CLDN6 in EC. METHODS: Firstly, the expression level of CLDN6 in EC was measured based on The...

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PMID: 30319275
DOI: 10.2147/ott.s174618

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