Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tight junction protein, claudin-6, downregulates the malignant phenotype of breast carcinoma.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 May 2010

Wu Qiong, Liu Yafang, Ren Yue, Xu Xiaoming, Yu Lina, Li Yulin, Quan Chengshi

Abstract excerpt

Claudin-6 is a protein component of tight junctions and its expression has been found to be undetectable or at low levels in some human and rat breast cancer cells. Here we investigated the effect of claudin-6 upregulation on the malignant phenotype of human MCF-7 breast cancer cells. MCF-7 subli...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Line, Tumor
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Claudins

Share to Down-Regulation

Share to Neoplasm Invasiveness

Share to Transfection

Source

Identifiers

PMID: 20215972
DOI: 10.1097/CEJ.0b013e328337210e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20215972-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tight junction protein, claudin-6, downregulates the malignant phenotype of breast carcinoma.PMID 20215972Read ↗

DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4AcSemantic proximity Read ↗

The role and mechanism of claudins in cancerSemantic proximity Read ↗

CLDN6 promotes chemoresistance through GSTP1 in human breast cancerSemantic proximity Read ↗

Emerging Roles of Claudins in Human CancerSemantic proximity Read ↗

Distinct claudin expression characterizes BRCA1-related breast cancer.Semantic proximity Read ↗

Emerging clinical significance of claudin-7 in colorectal cancer: a reviewSemantic proximity Read ↗

Claudin 1 in Breast Cancer: New InsightsSemantic proximity Read ↗

Low claudin-6 expression correlates with poor prognosis in patients with non-small cell lung cancerSemantic proximity Read ↗

Dysregulated expression of claudins in cancer (Review)Semantic proximity Read ↗

CLDN6-induced apoptosis via regulating ASK1-p38/JNK signaling in breast cancer MCF-7 cellsSemantic proximity Read ↗

Claudin-16 reduces the aggressive behavior of human breast cancer cells.Semantic proximity Read ↗

The Function of Oncogene B-Cell Lymphoma 6 in the Regulation of the Migration and Invasion of Trophoblastic CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.