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CLDN6: From Traditional Barrier Function to Emerging Roles in Cancers

14 Dec 2021

Abstract excerpt

Claudins (CLDNs) are the most important tight junction proteins, which are mainly expressed in endothelial cells or epithelial cells in a tissue-specific manner. As a member of the CLDNs family, CLDN6 is highly expressed in fetal tissues such as the stomach, pancreas, lung, and kidney, but is not expressed in corresponding adult tissues. The expression of CLDN6 is regulated by a variety of factors, including but...

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PMID: 34948213
DOI: 10.3390/ijms222413416

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