Back to search

Article

The Expression And The Tumor Suppressor Role of CLDN6 In Colon Cancer

2021-11-22

Abstract excerpt

<title>Abstract</title> <p>As a member of the tight junction family, CLDN6 is a tumor suppressor gene in breast cancer, but its role in colon cancer is unknown. In this research, we aimed at revealing the function of CLDN6 in colon cancer. We found that CLDN6 expressed lower in colon cancer tissues compared with adjacent normal tissues and the low expression of CLDN6 was correlated with lymph node metastasis. Sim...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5812bd1b-1358-58ca-90be-acd10971f51d
DOI
10.21203/rs.3.rs-1090058/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Expression And The Tumor Suppressor Role of CLDN6 In Colon CancerDOI 10.21203/rs.3.rs-1090058/v1
CLDN6: From Traditional Barrier Function to Emerging Roles in CancersSemantic proximity
Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-BSemantic proximity
Identification of Claudin-6 as a Molecular Biomarker in Pan-Cancer Through Multiple Omics Integrative AnalysisSemantic proximity
Identification of Key Claudin Genes Associated With Survival Prognosis and Diagnosis in the Colon Cancer Through Integrated Bioinformatic Analysis‏.Semantic proximity
The bioinformatics and experimental analysis of CD276 for prognosis and immune infiltrates in colon adenocarcinomaSemantic proximity
The Expression of CLDN6 in Hepatocellular Carcinoma Tissue and the Effects of CLDN6 on Biological Phenotypes of Hepatocellular Carcinoma CellsSemantic proximity
CLDN6 and CLDN10 are Associated with Immune Infiltration of Ovarian Cancer: A Study of Claudin FamilySemantic proximity
CRISPR/Cas9-Mediated Cldn2 Knockout in HCT116 Cells, Reveals Its Crucial Role in Colorectal Cancer progressionSemantic proximity
SNP Mutation‐related Genes in Colon Cancer for Monitoring and Prognosis of Patients: A Study Based on the TCGA DatabaseSemantic proximity
Identification of key claudin genes associated with survival prognosis and diagnosis in colon cancer through integrated bioinformatic analysisSemantic proximity
Comprehensive analysis of Distal-Less homeobox family gene expression in colon cancerSemantic proximity
DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.Semantic proximity
Select a neighboring publication to make it the new centre.