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Article

Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.

Neurobiology of aging - 1 Oct 2016

Neuner Sarah M, Garfinkel Benjamin P, Wilmott Lynda A, Ignatowska-Jankowska Bogna M, Citri Ami, Orly Joseph, Lu Lu, Overall Rupert W, Mulligan Megan K, Kempermann Gerd, Williams Robert W, O'Connell Kristen M S, Kaczorowski Catherine C

Abstract excerpt

An individual's genetic makeup plays an important role in determining susceptibility to cognitive aging. Identifying the specific genes that contribute to cognitive aging may aid in early diagnosis of at-risk patients, as well as identify novel therapeutics targets to treat or prevent development of symptoms. Challenges to identifying these specific genes in human studies include complex genetics, difficulty in...

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PMID: 27460150
DOI: 10.1016/j.neurobiolaging.2016.06.008
PMCID: PMC5018442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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