Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prominent hippocampal CA3 gene expression profile in neurocognitive aging.

Neurobiology of aging - 1 Sept 2011

Haberman Rebecca P, Colantuoni Carlo, Stocker Amy M, Schmidt Alexandra C, Pedersen Jan T, Gallagher Michela

Abstract excerpt

Research in aging laboratory animals has characterized physiological and cellular alterations in medial temporal lobe structures, particularly the hippocampus, that are central to age-related memory deficits. The current study compares molecular alterations across hippocampal subregions in a rat model that closely mirrors individual differences in neurocognitive features of aging humans, including both impaired...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Brain Chemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CA1 Region, Hippocampal

Share to Cognition Disorders

Share to Dentate Gyrus

Share to Memory Disorders

Share to Neuronal Plasticity

Share to Rats, Long-Evans

Source

Open in PubMed Open full text

Identifiers

PMID: 19913943
DOI: 10.1016/j.neurobiolaging.2009.10.005
PMCID: PMC2891610

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prominent hippocampal CA3 gene expression profile in neurocognitive aging.PMID 19913943Read ↗

Hippocampal Subregions Exhibit Both Distinct and Shared Transcriptomic Responses to Aging and Nonneurodegenerative Cognitive DeclineSemantic proximity Read ↗

Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive ImpairmentSemantic proximity Read ↗

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive ImpairmentSemantic proximity Read ↗

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory ImpairmentSemantic proximity Read ↗

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice.Semantic proximity Read ↗

Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48Semantic proximity Read ↗

Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's diseaseSemantic proximity Read ↗

Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through agingSemantic proximity Read ↗

Glucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations With AgingSemantic proximity Read ↗

Age- and ApoE Genotype-Dependent Transcriptomic Responses to O3 in the Hippocampus of Mice.Semantic proximity Read ↗

Evolution of the Aging Brain Transcriptome and Synaptic RegulationSemantic proximity Read ↗

Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional SignaturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.