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Article

Secondary structure impacts patterns of selection in human lncRNAs.

BMC biology - 25 Jul 2016

Pegueroles Cinta, Gabaldón Toni

Abstract excerpt

BACKGROUND: Metazoans transcribe many long non-coding RNAs (lncRNAs) that are poorly conserved and whose function remains unknown. This has raised the questions of what fraction of the predicted lncRNAs is actually functional, and whether selection can effectively constrain lncRNAs in species with small effective population sizes such as human populations. RESULTS: Here we evaluate signatures of selection in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27457204
DOI: 10.1186/s12915-016-0283-0
PMCID: PMC4960838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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