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Article

Patterns of variation in cis-regulatory regions: examining evidence of purifying selection.

BMC genomics - 26 Jan 2018

Naidoo Thijessen, Sjödin Per, Schlebusch Carina, Jakobsson Mattias

Abstract excerpt

BACKGROUND: With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much debate. This has gained further impetus in recent years due to a rapidly growing catalogue of genomic elements, based primarily on biochemical signatures (e.g. the ENCODE project). While the assessment of functionality is a complex task, the presence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29373957
DOI: 10.1186/s12864-017-4422-y
PMCID: PMC5787233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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