Article

Sequence alignment of the primate lineage reveals evolutionary divergence and conserved secondary structural motifs in noncoding RNAs

2026-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Long noncoding RNAs (lncRNAs) constitute most of the human transcriptome and perform essential roles in chromatin organization and transcriptional regulation. Because lncRNA genes are not constrained by protein-coding ability, they tend to exhibit more rapid evolutionary divergence. Their poor nucleotide sequence conservation among mammals often led to the assumption that lncRNAs lack conserved...

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Literature Corpus work: 16b8b546-ad88-5931-92ce-2708d561f376
DOI: 10.64898/2026.05.18.725462

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