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Article

Mutations within lncRNAs are effectively selected against in fruitfly but not in human.

Genome biology - 27 May 2013

Haerty Wilfried, Ponting Chris P

Abstract excerpt

BACKGROUND: Previous studies in Drosophila and mammals have revealed levels of long non-coding RNAs (lncRNAs) sequence conservation that are intermediate between neutrally evolving and protein-coding sequence. These analyses compared conservation between species that diverged up to 75 million years ago. However, analysis of sequence polymorphisms within a species' population can provide an understanding of...

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Share to Conserved Sequence
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

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Share to RNA, Long Noncoding

Share to Selection, Genetic

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 23710818
DOI: 10.1186/gb-2013-14-5-r49
PMCID: PMC4053968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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