Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency

21 Jul 2016

Abstract excerpt

Induced pluripotent stem cells (iPSCs) represent an innovative source for the standardized in vitro generation of macrophages (Mφ). We here describe a robust and efficient protocol to obtain mature and functional Mφ from healthy as well as disease-specific murine iPSCs. With regard to morphology, surface phenotype, and function, our iPSC-derived Mφ (iPSC-Mφ) closely resemble their counterparts generated in vitro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neonatal Respiratory Health Research
Share to Renal and related cancers
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27453007
DOI: 10.1016/j.stemcr.2016.06.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb DeficiencyPMID 27453007Read ↗

Use of Induced Pluripotent Stem Cells to Recapitulate Pulmonary Alveolar Proteinosis PathogenesisSemantic proximity Read ↗

Gene Correction of Human Induced Pluripotent Stem Cells Repairs the Cellular Phenotype in Pulmonary Alveolar ProteinosisSemantic proximity Read ↗

Production and Characterization of Human Macrophages from Pluripotent Stem Cells.Semantic proximity Read ↗

Human Induced Pluripotent Stem Cell-Derived Macrophages for Unraveling Human Macrophage Biology.Semantic proximity Read ↗

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.Semantic proximity Read ↗

Adaptation of Human iPSC-Derived Macrophages Toward an Alveolar Macrophage-Like Phenotype Post-Intra-Pulmonary Transfer into Murine Models.Semantic proximity Read ↗

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis.Semantic proximity Read ↗

ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophagesSemantic proximity Read ↗

TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosisSemantic proximity Read ↗

Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment.Semantic proximity Read ↗

Pulmonary macrophage transplantation therapy.Semantic proximity Read ↗

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.