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Article

Polymorphisms of APLN-APLNR system are associated with essential hypertension in Mexican-Mestizo individuals.

Experimental and molecular pathology - 1 Aug 2016

Esteban-Martínez Rosa Lilia, Pérez-Razo Juan Carlos, Vargas-Alarcón Gilberto, Martínez-Rodríguez Nancy, Cano-Martínez Luis Javier, López-Hernández Luz Berenice, Rojano-Mejía David, Canto Patricia, Coral-Vazquez Ramón Mauricio

Abstract excerpt

The aim of this study was to evaluate if polymorphisms of APLN and APLNR genes may play a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients. A case-control study was carried out including normotensive and hypertensive individuals. For these, two polymorphisms of APLN (rs3761581 and rs56204867) and two of APLNR () genes were genotyped by 5' exonuclease TaqMan assay in 400...

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Source

Identifiers

PMID: 27450650
DOI: 10.1016/j.yexmp.2016.07.007

Genes

APLNR
APLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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