Article
[Association of the polymorphisms of sodium transport related genes with essential hypertension].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2009
Gong Ping-yuan, Shen Guo-min, Peng He-mei, Luo Yan, Shen Yan, Zhao Xiao
Abstract excerpt
OBJECTIVE: To investigate the association of the polymorphisms of rs4961 in alpha-adducin (ADD1) and rs28933400 in Na+/K+ -ATPase a2 (ATP1A2) genes, the products of which are important for sodium transport, with essential hypertension. METHODS: Mutagenically separated PCR (MS-PCR) was used to detect the genotypes of the two loci. The subjects were recruited randomly including 196 patients of essential...
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