Article
Microsatellite DNA polymorphism of human adrenomedullin gene in normotensive subjects and patients with essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 2001
Ishimitsu T, Hosoya K, Tsukada K, Minami J, Futoh Y, Ono H, Ohrui M, Hino J, Kangawa K, Matsuoka H
Abstract excerpt
Adrenomedullin (AM) is a hypotensive peptide widely produced in the cardiovascular organs and tissues. We have cloned and sequenced the genomic DNA encoding the human AM gene and have determined that the gene is located in the short arm of chromosome 11. The 3'-end of the gene is flanked by the m...
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