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Article

Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients.

Oncotarget - 16 Aug 2016

Hsu Kuo-Hsuan, Tseng Jeng-Sen, Wang Chih-Liang, Yang Tsung-Ying, Tseng Chien-Hua, Chen Hsuan-Yu, Chen Kun-Chieh, Tsai Chi-Ren, Yang Cheng-Ta, Yu Sung-Liang, Su Kang-Yi, Yu Chong-Jen, Ho Chao-Chi, Hsia Te-Chun, Wu Ming-Fang, Chiu Kuo-Liang, Liu Chien-Ming, Yang Pan-Chyr, Chen Jeremy J W, Chang Gee-Chen

Abstract excerpt

Despite the advancement of epidermal growth factor receptor (EGFR) inhibitors in lung cancer therapy, it remains unclear whether EGFR mutation status in familial lung cancers is different from that of sporadic cases. In this multicenter retrospective study, we compared both the EGFR mutation frequency and patterns between familial and sporadic cases. The results explored that family history of lung cancer is an...

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Identifiers

PMID: 27449093
DOI: 10.18632/oncotarget.10715
PMCID: PMC5288187

Genes

EGFR
YAP1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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