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Characterization of germline mutations in familial lung cancer from the Chinese population.

Gene - 30 Jan 2018

Kanwal Madiha, Ding Xiao-Jie, Ma Zhans-Han, Li Lian-Wei, Wang Ping, Chen Ying, Huang Yun-Chao, Cao Yi

Abstract excerpt

Compared with numerous studies of somatic mutations using sporadic lung cancer, the research into germline mutations using familial lung cancer (FLC) is limited. In the present study, we used FLC samples obtained from the Chinese population in highly air-polluted regions to screen for novel germline mutations in lung cancer. Through a whole genome sequencing (WGS) analysis of the nine subjects (four lung cancer...

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Source

Identifiers

PMID: 29054765
DOI: 10.1016/j.gene.2017.10.020

Genes

ARHGEF5
MUC12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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