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Presentation of EGFR mutations in 162 family probands with multiple primary lung cancer

1 Apr 2021

Abstract excerpt

Background: The number of multiple primary lung cancer (MPLC) patients has rapidly increased in recent years. However, information regarding the etiology of MPLC and responsiveness to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is rare. The present study aims to describe the mutation signatures of EGFR in MPLC.Methods: Polymerase chain reaction (PCR) and Sanger sequencing were used...

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PMID: 34012789
DOI: 10.21037/tlcr-20-1001

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