Article
Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review.
BMC cancer - 8 Nov 2019
Cheng Yue I, Gan Yun Cui, Liu Dan, Davies Michael P A, Li Wei Min, Field John K
Abstract excerpt
BACKGROUND: Accumulating evidence indicates inherited risk in the aetiology of lung cancer, although smoking exposure is the major attributing factor. Family history is a simple substitute for inherited susceptibility. Previous studies have shown some possible yet conflicting links between family history of cancer and EGFR mutation in lung cancer. As EGFR-mutated lung cancer favours female, never-smoker,...
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